Syndrome de Kallmann
نویسندگان
چکیده
منابع مشابه
Kallmann syndrome: MR findings.
PURPOSE To evaluate patients with known hypogonadotropic hypogonadism, some with known anosmia, for defective rhinocephalon development that resulted in olfactory tract abnormalities, an affliction known as Kallmann syndrome. METHODS Six patients who clinically had hypogonadotropic hypogonadism were examined by MR. Thin coronal images of the interior frontal region were used to determine pres...
متن کاملMRI findings in Kallmann syndrome.
Kallmann syndrome (KS) is a neuronal migration disorder characterised by hypogonadotrophic hypogonadism and anosmia or hyposmia. Five patients with clinical findings suggestive of KS were evaluated with MRI. All patients had abnormalities of olfactory system. Olfactory bulbs were absent in all patients. Olfactory sulci were absent in 3 patients and hypoplastic in 2 patients. Anterior pituitary ...
متن کاملBrain changes in Kallmann syndrome.
BACKGROUND AND PURPOSE Kallmann syndrome is a rare inherited disorder due to defective intrauterine migration of olfactory axons and gonadotropin-releasing hormone neurons, leading to rhinencephalon hypoplasia and hypogonadotropic hypogonadism. Concomitant brain developmental abnormalities have been described. Our aim was to investigate Kallmann syndrome-related brain changes with conventional ...
متن کاملBringing Kallmann syndrome into focus.
Three articles ( 1-3) in this issue of AJNR bring the power of magnetic resonance (MR) to bear on the problem of neuroimaging in Kallmann syndrome (KS). These investigators provide the most detailed views of KS olfactory pathology that can be obtained outside of the anatomy laboratory, opening a new window on the study of this disease. The principle phenotypic features of KS, anosmia and hypogo...
متن کاملPROK2/PROKR2 Signaling and Kallmann Syndrome
Kallmann syndrome (KS) is a developmental disease that associates hypogonadism and a deficiency of the sense of smell. The reproductive phenotype of KS results from the primary interruption of the olfactory, vomeronasal, and terminal nerve fibers in the frontonasal region, which in turn disrupts the embryonic migration of neuroendocrine gonadotropin-releasing hormone (GnRH) synthesizing cells f...
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ژورنال
عنوان ژورنال: médecine/sciences
سال: 2011
ISSN: 0767-0974,1958-5381
DOI: 10.1051/medsci/2011272135